Main duties and responsibilities include: Demonstrating strong knowledge of the clinical disease state and treatment guidelines and effectively engaging with stakeholders in clinical discussions to inform access strategy for the CVRM pipeline. Partnering with Brand teams to shape customer communication strategies for the CVRM pipeline and develop promotional assets that reflect access priorities and value messaging including pull-through materials and negotiation frameworks. Contributing to the development and implementation of a cohesive communication strategy for the CVRM pipeline across payer, provider, and patient audiences to drive clarity on product value. Developing compelling product value propositions and value strategies for the CVRM pipeline across market access channels, including payers, IDNs, pharmacies, distributors, and policy stakeholders. Partnering to recommend pricing and compliant payer contracting approaches aligned with brand P&L, including innovative approaches to evolving market challenges and contributing to the continuous improvement of market access strategies and execution. Leading in the design and implementation of affordability programming that ensures patient access while carefully stewarding brand budget and gross-to-net impact. Applying advanced understanding of the US market access landscape and the legal/regulatory environment to ensure compliant, effective messaging and tactics. Leading research and generating insights to inform market access messaging, evidence needs, and customer engagement plans. Leading payer research and landscape assessments to inform scenario planning, launch readiness, and risk mitigation for the CVRM pipeline across all segments.

The ideal candidate will have a Bachelor's degree and 3+ years of experience in one or a combination of pharmaceutical, healthcare, scientific, clinical, institutional or related industry or commercial experience. An advanced degree in Business, Marketing, or Science is desirable. The candidate should demonstrate learning agility, experience developing and executing strategy, managed care/payer experience, and teamwork and leadership skills.

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The Director, US Forecasting & Analytics – Vaccines & Immune Therapies is a senior commercial insights leader responsible for US demand forecasting and analytics across the V&I portfolio. The role is predominantly forecast-focused, serving as the US forecasting lead and strategic thought partner to Marketing, Finance, Market Access, and US teams.

Responsibilities:

US Forecasting Leadership (Core Accountability)

• Lead US short-term and long-term demand forecasts (TRx, NBRx, volume, patients, revenue) for V&I assets using robust, patient-based and market-based models
• Own forecast methodology, assumptions, and governance, ensuring objectivity, transparency, and consistency with enterprise standards
• Integrate primary market research, epidemiology, competitive intelligence, access dynamics, and real-world data into forecast models
• Proactively identify and quantify key risks and opportunities through scenario and sensitivity analyses
• Partner closely with Finance, Market Access & Pricing, Marketing, Sales, Medical, and Global Forecasting to ensure alignment on assumptions and implications
• Support business planning, governance reviews, and opportunity assessments with clear, executive-ready narratives
• Serve as a trusted advisor to senior marketing and finance leadership, clearly articulating forecast drivers and changes

Analytics & Resource Leadership (Enablement)

• Provide leadership over forecasting-adjacent analytics, ensuring advanced analytics and insights are embedded into forecasting and business planning
• Manage and prioritize internal analysts, contractors, and external vendors supporting forecasting and analytics deliverables
• Partner with data analytics resources, Global IA&F, and GIBEX capability teams to deploy new tools, data sources, and modeling approaches
• Champion and identify new ways to embed AI and advanced automation into the practice of data analytics and forecasting to drive efficiency, scalability, and decision quality
• Champion continuous improvement in forecasting processes, AI-enabled modeling, and automation
• Contribute to the development and sharing of best practices across the V&I forecasting community

Essential for the role

• Bachelor’s degree in a quantitative, scientific, or business-related field required (e.g., Statistics, Economics, Mathematics, Engineering, Computer/Data Science).
• 8+ years’ experience in US pharmaceutical commercial forecasting, including in-market and late-stage pipeline assets
• Hands-on model ownership experience (build, refresh, and performance tracking) across short- and long-term horizons
• Expertise in scenario-based forecasting, sensitivity analysis, and driver-based narratives to support senior decision-making
• Strong capability integrating multiple data types (e.g., IQVIA, claims, epidemiology, RWD/RWE, primary research) into coherent, decision-grade forecasts
• Working knowledge of advanced analytics/ML approaches (e.g., time series, causal inference, ensembles) and where they add value vs. traditional methods
• Fluency in modern analytics tooling and automation (e.g., Python/R/SQL, BI/visualization), with ability to partner effectively with data engineering and analytics teams
• Demonstrated forecast governance and model risk discipline (traceable assumptions, documentation, and clear explanations)
• Strong understanding of US market access and payer dynamics and how they impact demand (coverage, contracting, channel, policy)
• Exceptional communication: translates complex analysis into clear, executive-ready insights, options, and recommendations
• Strong commercial competence across key demand levers (positioning, adoption, competitive dynamics, lifecycle events)

Desirable for the role

• Advanced degree preferred (e.g., MBA, MS, PhD in Statistics, Economics, Decision Sciences, Data Science, or related discipline).
• Vaccines and/or Rare Disease experience, including familiarity with immunization dynamics, patient-based forecasting, and lifecycle management in preventive or immune-mediated therapies
• Change leadership: builds adoption for new tools, processes, and ways of working across cross-functional stakeholders
• Product mindset for forecasting: defines user needs, success metrics, and a roadmap for portfolio forecasting capabilities
• Model lifecycle practices (e.g., reproducibility, versioning, monitoring/drift awareness); familiarity with MLOps concepts

Office Working Requirements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

#LI-Hybrid

Date Posted 10-Apr-2026 Closing Date 23-Apr-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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The successful candidate will thrive in a rapidly changing market access environment, create clear goals and inspiring plans, develop strong partnerships, and make difficult decisions. You will manage all marketing activities for the CVRM pipeline to support company objectives. You will conduct analyses of the market segment, including identification of key growth drivers, opportunities, and risks. You will incorporate results of analysis into product strategy.

Key responsibilities include:

• Demonstrating expert knowledge and understanding of the clinical disease state to inform value strategy and access planning.
• Leading the development of customer education materials and tactics to effectively execute the market access strategy for the CVRM pipeline across stakeholders.
• Translating scientific and clinical evidence into clear market value propositions that resonate with payers, providers, and policy stakeholders.
• Creating an integrated payer insight, evidence generation, and customer engagement plan to support access, reimbursement, and pull-through for the CVRM pipeline.
• Aligning closely with brand teams to develop product value propositions and comprehensive value strategies across market access channels.
• Partnering to recommend pricing and compliant payer contracting approaches aligned with brand P&L, including innovative approaches to evolving market challenges and contributing to the continuous improvement of market access strategies and execution.
• Leading in the design and implementation of affordability programming that ensures patient access while carefully stewarding brand budget and gross to net impact.
• Maintaining expert understanding of the US market access landscape, including legal, regulatory, and compliance requirements affecting coverage and reimbursement.
• Applying strong financial acumen to understand US payer deal/no-deal analysis, informing contracting strategies and sustainable access decisions.
• Developing robust measurement, analytics, and reporting plans to track performance, optimize tactics, and inform strategy evolution.
• Leading and contributing to innovative approaches to meet evolving market access requirements, leveraging insights, data, and external trends.
• Communicating brand aspiration and market access strategy to key field-based Market Access teams, enabling flawless execution and alignment.

Essential requirements include:

• Bachelor's degree
• 5+ years of experience in one or a combination of pharmaceutical, healthcare, scientific, clinical, institutional, or related industry experience
• 3 years of commercial experience
• Understanding of the US market access landscape and the legal/regulatory environment for pharmaceuticals/healthcare industry required

Desirable requirements, skills, and capabilities include:

• Advanced degree in business, marketing, or science
• Experience in customer-facing roles
• Financial and forecasting experience
• Proven track record of consistent achievement or overachievement in developing and delivering strategic and operational plans within a therapeutic or business area
• Demonstrated experience in working within cross-functional business units essential
• Strong financial acumen with the ability to assess and drive results
• Strong communication, presentation, collaboration, and negotiation skills
• Ability to successfully lead through change, complexity, and ambiguity in a highly matrixed environment
• Demonstrated learning agility

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