Introduction to role

At AstraZeneca, teams work across global boundaries to make an impact and find answers to complex challenges. This role sits at the heart of that mission, combining scientific depth with strategic leadership to advance care in chronic respiratory disease. As US Head of Medical, COPD, this position owns the medical strategy and execution for a novel Interleukin-33 targeting monoclonal antibody, crafting both product and disease area direction across the full lifecycle. Reporting directly to the VP Medical Respiratory, Immunology, Vaccines and Immune Therapies (R&I), this leader will guide a high-performing team, drive launches, and influence how evidence, access and clinical practice come together to transform outcomes for patients living with COPD and severe lower respiratory tract disease. Ready to steer a first-in-class biologic and redefine what’s possible in respiratory medicine?

Accountabilities

• Lead and grow the COPD US medical team, setting clear vision, priorities and standards for excellence in disease area and brand strategy and execution.
• Develop and deliver coordinated medical strategies and plans for COPD and related indications, ensuring alignment with global medical, US commercial and market access partners.
• Develop and implement Transforming Healthcare initiatives that shape the biologics market in COPD, severe LRTD and adjacent areas, using evidence and insight to influence clinical practice and care pathways.
• Own disease area and brand medical budgets and resource planning, ensuring optimal allocation to high-impact activities across the lifecycle.
• Co-lead the COPD Core Value Team with Commercial and Market Access leaders, connecting strategy, science, access and execution to deliver a cohesive launch plan.
• Continuously assess and communicate the competitive landscape, translating insights into differentiated positioning and tactical plans.
• Act as the primary US medical point of contact for the Global Product Team (GPT), providing strategic input on lifecycle management, phase IV strategy and study design.
• Partner with evidence generation teams to define and execute real-world evidence programs that address US clinical, payer and policy needs.
• Build and sustain positive relationships with external authorities, professional societies, patient groups and key internal stakeholders to inform strategy and amplify scientific leadership.
• Serve as a medical spokesperson for COPD in response to media inquiries when required, ensuring accurate, balanced and compliant communication.
• Coach, mentor and develop direct reports, actively leading succession, talent development and engagement within the team.
• Nurture a culture that values scientific rigor, teamwork, innovation and recognition, while maintaining full compliance with AstraZeneca policies and external regulations.

Essential Skills/Experience

• Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
• A Minimum of 7 years of experience in the pharmaceutical industry, ideally in Medical Affairs, working at the country and global/regional level
• Medical/clinical/scientific expertise in Respiratory Disease
• Experienced team leader, with a track record of establishing high performance teams
• Demonstrated track record delivering results in a sophisticated matrix environment, building capabilities, and leading impactful medical initiatives. Experience launching a new product
• US Regulatory Strategy Knowledge including product approval, label requirements/ negotiation
• Consistent track record to collaborate and build internal and external networks
• Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment

Desirable Skills/Experience

• Leadership experience in US Medical Affairs for respiratory biologics or other specialty therapeutics.
• Direct involvement in major US product launches in COPD or related respiratory indications.
• Experience crafting or overseeing real-world evidence programs passionate about payer needs and healthcare system impact.
• Background working closely with field medical teams and external authorities to develop standards of care.
• Track record influencing cross-functional investment decisions using medical insights and data.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an environment where medical leaders sit at the intersection of science and real-world practice, using evidence to influence how care is delivered today and tomorrow. Work alongside experts who embrace change because it sparks innovation, from bold real-world studies to pioneering launches that shift treatment paradigms in respiratory disease. Collaboration across research, medical and commercial functions is embedded in how things get done here, opening doors to new ideas, broader networks and continuous development without borders. Every study designed, every partnership built and every insight translated into practice contributes directly to better outcomes for patients and fuels the next wave of scientific progress.

If this opportunity to lead COPD medical strategy in the US excites you, apply now and take the next step in your career with AstraZeneca.

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Platform Solutions & Content Solutions

Platform Solutions is Millennium's rapidly evolving organization that leverages technology to deliver intelligence and resources to our investment professionals at scale. Within Platform Solutions, Content Solutions provides proprietary expertise and insights on data, independent research, and investment tools.

As a Content Analyst, you will build deep expertise in content relevant to Global Systematic Strategies and publish your insights to investment professionals across the firm. You will proactively identify, vet, recommend, and onboard new high-value content to advance the investment process. You will work cross-functionally with Corporate Access, Broker Relations, and other key internal stakeholders to carve out a distinct value proposition within Global Systematic Strategies.

Your role will involve constant innovation, testing new approaches, learning from outcomes, and executing with precision. By leveraging creativity, collaboration, and a strategic mindset, you will contribute to the evolution of Platform Solutions and create a measurable impact across the firm.

Responsibilities:

Content Discovery and Analysis - Research, discover, and vet data and research products to formulate a view on their potential value for investment professionals - Stay informed of industry trends, changes to known products, and new products not yet in use at the firm - Build and maintain detailed documentation on providers and products within your focus area - Author and publish proprietary commentary and reports on content within your focus area to drive value to investment professionals - Leverage your expertise to optimize the firm's portfolio of data and research within your focus area; onboard new high-value products at best-in-class pricing, offboard inferior products, and guide investment professionals toward the best products for their strategy

Innovation and Strategic Impact - Continuously evaluate and enhance the processes for sourcing, vetting, and delivering content to investment professionals at scale; test new approaches and learn from outcomes to refine and improve workflows - Develop and execute a unique value proposition for your role within Content Solutions, ensuring alignment with the needs of investment professionals and the broader platform - Build deep knowledge of data, independent research, and investment tools relevant to Global Systematic Strategies, becoming the firm's subject matter expert

Cross-Functional Collaboration - Partner with investment professionals to understand their unique processes and recommend tailored content solutions; learn from their insights and feedback to continuously improve the firm's content platform and portfolio - Collaborate with the Broker Data Analyst in Content Solutions to develop and deliver a holistic view of content for Global Systematic Strategies from brokers and other providers - Work closely with Corporate Access and Broker Relations to identify synergies and deliver innovative solutions that enhance the PSEM platform - Coordinate with internal counterparts, including business management, data science and engineering, legal, compliance, and operations, to optimize the firm's content platform

Building Strategic Relationships - Develop 1x1 relationships with investment professionals to understand their unique strategies and content needs - Market the content platform to prospective and new investment professionals, onboarding them to the platform and ensuring they understand its value - Establish and maintain strategic relationships with content providers, generating unique opportunities to access high-value content for investment professionals - Negotiate commercial and business terms with content providers to achieve best-in-class pricing and position for scale

Operational Excellence and Process Optimization - Manage high volumes of work across diverse functions and competing priorities, ensuring effective communication and timely execution - Leverage and contribute to the development of internal technology to improve workflows and the investment professionals' experience - Develop frameworks for tracking and evaluating the success of Content Solutions, using data-driven insights to inform decision-making

Qualifications/Skills Required:

Analytical Skills: Strong analytical and critical thinking skills, with the ability to assess the value and relevance of new products in order to formulate a viewpoint - Communication Skills: Strong written and verbal communication skills, with the ability to present ideas clearly and persuasively - Innovative Mindset: A passion for challenging existing processes, experimenting with new ideas, and driving continuous improvement - Cross-Functional Collaboration: Proven ability to work effectively across diverse teams in order to deliver value for the organization - Relationship Management: Strong interpersonal skills and the ability to build strategic relationships with investment professionals and content providers - Adaptability and Resilience: Comfortable with ambiguity, with the ability to operate independently and learn from failures while maintaining a results-oriented approach - Organizational Skills: Excellent time management and organization skills to manage high volumes of work effectively - Data Analytics & Acumen: Strong data literacy with the ability to assess data quality, understand data science concepts, and leverage insights to inform decision-making and optimize workflows - Strategy Knowledge: Familiarity with systematic investment processes and an understanding of what makes datasets valuable to quantitative strategies - Experience: 6+ years of professional experience in finance, data, and/or research

Millennium is a total compensation organization where you will be eligible for a base salary, discretionary performance bonus, and a comprehensive benefits package. The estimated base salary range for this position is $160,000 to $250,000, which is specific to New York and may change in the future. When finalizing an offer, we take into consideration an individual's experience level and the qualifications they bring to the role to formulate a competitive total compensation package.

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