The Head of Gynaecological Cancers, Senior Global Medical Affairs Leader turns therapy area strategy into scalable, high-quality execution across a sophisticated cluster of indications and assets. This role leads 5–6 Sr GMAL/GMALs who each own 1–2 indications, ensuring the ten core GMAL accountabilities are delivered consistently. The Global Medical Head sets direction, governs quality, and ensures compliant, efficient, and high-impact medical execution globally in support of an anticipated ~60 launches over three years across five tumor areas.
\nReady to develop how evidence, insight, and strategy come together to redefine cancer care?
\nProvide indication and asset leadership by translating therapy area priorities into clear indication strategies, setting direction and making evidence-based trade-offs across the cluster to benefit global medical objectives, acting as final escalation point for sophisticated benefit-risk and reputational decisions.
\nDrive global medical strategy through cross-functional engagement by ensuring Sr GMAL/GMALs consistently lead key forums with markets, and by standardising operating cadences that align Development, Regulatory, Pharmacovigilance, Access, and non-promotional Commercial teams around the medical plan.
\nLead all aspects of evidence generation governance by mentoring and approving indication evidence plans that address the most critical gaps, crafting strategy and develop of medical evidence (Phase IV, pragmatic studies, registries, RWE, IIS) and guiding operational support to deliver on time and on budget.
\nShare accountability for publications by partnering with Publications on cluster publication strategies, endorsing prioritisation, authorship plans and timelines, securing GPT/GPL endorsement, and ensuring scientific integrity and compliance with GPP/ICMJE.
\nLead the cross-indication scientific narrative by ensuring Sr GMAL/GMALs lead coherent narratives and confidence-building strategies that are consistent across channels, geographies, and lifecycle stages.
\nDefine medical education priorities at cluster level and provide subject-matter guidance so medical training and communications teams can design, develop, and deliver education aligned to the scientific platform.
\nDirect external engagement and partnerships strategy across indications, being responsible for execution with KEEs, societies, and appropriate partners in alignment with MESO on partnership frameworks and governance.
\nLead congress strategy by defining the cross-indication congress plan, guiding symposia strategy, abstracts, booth scientific narratives, compliant engagements, and ensuring magnificent execution and robust post-congress insight collection.
\nEnable regions and integrate insights by sponsoring toolkits, core content, and training, establishing closed-loop insight systems so market feedback rapidly updates strategy, studies, and content.
\nDrive operational excellence by leading the cluster budget and vendor ecosystem, setting standards for medical planning, dashboards, risk and issue management, and MLR processes, while optimising FTE allocation across Sr GMAL/GMAL teams based on launch timing and complexity.
\nLead risk, safety, and compliance by anticipating scientific and safety risks, partnering with Pharmacovigilance on signals, RMPs, and labeling updates, and upholding medical governance, promotional separation, and audit-ready documentation.
\nAct as an enterprise integrator by serving as senior medical counterpart to Development, Regulatory/Labeling, PV, HEOR/Market Access, Diagnostics/CDx, Digital, Manufacturing and regional medical leaders, aligning with MESO on partnerships and medical excellence standards.
\nXML job scraping automation by YubHub
","url":"https://yubhub.co/jobs/job_494cee6c-3a3","directApply":true,"hiringOrganization":{"@type":"Organization","name":"GU/GYN","sameAs":"https://astrazeneca.eightfold.ai","logo":"https://logos.yubhub.co/astrazeneca.eightfold.ai.png"},"x-apply-url":"https://astrazeneca.eightfold.ai/careers/job/563877690010089?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply","x-work-arrangement":"hybrid","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$285,873 - $428,809","x-skills-required":["MBBS","MD","PhD","PharmD","oncology specialty training","extensive oncology leadership experience","global launch success","portfolio prioritization","evidence-based decision making","executive influence","stakeholder negotiation","change leadership","talent development","scientific communication","ICH/GCP","PV processes","GPP/ICMJE","global industry codes"],"x-skills-preferred":["proven track record of orchestrating sophisticated launch portfolios","experience building or transforming high-performing medical teams","proven impact in shaping clinical practice or guidelines","strong record of partnership with Development and Commercial","comfort operating in fast-paced environments"],"datePosted":"2026-04-25T14:08:03.471Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Gaithersburg, Maryland, United States of America"}},"employmentType":"FULL_TIME","occupationalCategory":"Medical","industry":"Healthcare","skills":"MBBS, MD, PhD, PharmD, oncology specialty training, extensive oncology leadership experience, global launch success, portfolio prioritization, evidence-based decision making, executive influence, stakeholder negotiation, change leadership, talent development, scientific communication, ICH/GCP, PV processes, GPP/ICMJE, global industry codes, proven track record of orchestrating sophisticated launch portfolios, experience building or transforming high-performing medical teams, proven impact in shaping clinical practice or guidelines, strong record of partnership with Development and Commercial, comfort operating in fast-paced environments","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":285873,"maxValue":428809,"unitText":"YEAR"}}},{"@context":"https://schema.org","@type":"JobPosting","identifier":{"@type":"PropertyValue","name":"YubHub","value":"job_aa94a8fc-438"},"title":"Global Clinical Head, Respiratory","description":"The Global Clinical Head (GCH) is the most senior medical scientific expert on an asset/product/indication team and is a core member of the Franchise Team (if applicable) and/or the Global Product Team (GPT).
\nThis role will report to the Vice President Clinical Respiratory.
\nKey responsibilities include:
\nEssential qualifications include:
\nDesirable qualifications include:
\nJoin AstraZeneca in our journey of building a new kind of organization to reset expectations of what a biopharmaceutical company can be. We are committed to delivering life-changing medicines and making a positive impact on people's lives.
\nThe annual base salary for this position ranges from $331,873 - $497,810. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
\nIn addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program.
\nBenefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.
\nAdditional details of participation in these benefit plans will be provided if an employee receives an offer of employment.
\nIf hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
\nXML job scraping automation by YubHub
","url":"https://yubhub.co/jobs/job_aa94a8fc-438","directApply":true,"hiringOrganization":{"@type":"Organization","name":"Inhaled, ClinDev Respiratory","sameAs":"https://astrazeneca.eightfold.ai","logo":"https://logos.yubhub.co/astrazeneca.eightfold.ai.png"},"x-apply-url":"https://astrazeneca.eightfold.ai/careers/job/563877689960992?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply","x-work-arrangement":"hybrid","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$331,873 - $497,810","x-skills-required":["MD","Respiratory","Late-phase drug development","Clinical studies","Regulatory submissions","Patient risk management plans","Global regulatory submissions","Major regulatory agencies","Line management","Business acumen"],"x-skills-preferred":[],"datePosted":"2026-04-24T14:18:43.065Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Boston, Massachusetts, United States of America"}},"employmentType":"FULL_TIME","occupationalCategory":"Healthcare","industry":"Biotechnology","skills":"MD, Respiratory, Late-phase drug development, Clinical studies, Regulatory submissions, Patient risk management plans, Global regulatory submissions, Major regulatory agencies, Line management, Business acumen","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":331873,"maxValue":497810,"unitText":"YEAR"}}}]}