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You will contribute hands-on to experimental design, process characterization, and scale-up/tech transfer activities from research through IND enabling, partnering closely with Research, Analytical Development, CMC, Regulatory, Manufacturing, Quality, and external CDMOs.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>Plan and perform experiments to develop and optimize LVV upstream processes for suspension cell culture (transient or stable producer cell systems), targeting improvements in titer, quality, robustness, and cost.</li>\n</ul>\n<ul>\n<li>Execute unit operations across seed, production, and harvest interfaces; support scale-up strategies from bench to pilot and clinical scales; develop and use scale-down models for characterization and comparability.</li>\n</ul>\n<ul>\n<li>Design DOE studies, identify CPPs/CMAs, analyze data, and propose control strategies; document results in protocols and reports; maintain fit for-purpose knowledge records.</li>\n</ul>\n<ul>\n<li>Contribute to definition of design space, in-process controls, and operating ranges; trend process performance and drive troubleshooting, root cause analysis, and corrective actions.</li>\n</ul>\n<ul>\n<li>Prepare technical transfer packages and support transfers to internal GMP sites and CDMOs; align process documentation with cGMP principles for late-stage readiness.</li>\n</ul>\n<ul>\n<li>Work closely with Analytical Development on assay readiness and in process testing; partner with Manufacturing, Supply, and Quality to ensure operational feasibility and compliance.</li>\n</ul>\n<ul>\n<li>Apply Lean practices and digital tools for scheduling, data integrity, and reproducibility; track KPIs (titer, infectivity, impurity profiles, cycle time, right first time) and recommend improvements.</li>\n</ul>\n<p>Qualifications:</p>\n<ul>\n<li>Education: Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 1+ years of industry experience; OR M.S. with 4+ years; OR B.S. with 5+ years of hands-on industry experience.</li>\n</ul>\n<ul>\n<li>Experience: Hand-on experience developing suspension-based LVV upstream processes; 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You will be responsible for overseeing the day-to-day operations of the new facility, ensuring the efficient and high-quality processing of mineral exploration samples (ex. soil and stream sediment).</p>\n<p>Your responsibilities will include:</p>\n<ul>\n<li>Laboratory management: ensuring safe and efficient operation of the laboratory</li>\n<li>Teamwork: serving as a hands-on team leader, clearly communicating hazards and opportunities for improvement</li>\n<li>Overseeing analytic workflow: ensuring adherence to effective operating procedures that guide sample preparation, instrument operation, sample archiving, and data storage</li>\n<li>Process optimization: continuously evaluating and improving sample preparation and measurement procedures (washing, loading, and automated analysis with analytic instruments) to increase efficiency, precision, and turnaround time</li>\n<li>Quality assurance/quality control (QA/QC): operating and maintaining rigorous QA/QC protocols, utilizing specialized software to track every sample through each stage of the process, ensuring data integrity and traceability</li>\n<li>Equipment maintenance: overseeing the maintenance and calibration of all laboratory equipment, minimizing downtime</li>\n<li>Stakeholder communication: reporting on laboratory performance, capacity, and quality metrics to the exploration and operations leadership teams</li>\n</ul>\n<p>You must have:</p>\n<ul>\n<li>At least 5 years of laboratory experience in mineral exploration &amp; mining, oil &amp; gas, or a related industry</li>\n<li>Proven, extensive experience in operating a commercial or exploration mineral laboratory, with a focus on instrumentation for geochemical analysis such as laboratory balances, microscopes, and spectrometers</li>\n<li>Experience with sample preparation methods for various sample types (soil, sediment, rock/drill core)</li>\n<li>A track record of identifying inefficiencies and suggesting or implementing process improvements in a laboratory or operational environment</li>\n<li>Demonstrated commitment to and familiarity with developing and implementing high standards of health &amp; safety in the workplace</li>\n<li>A high degree of independence and the ability to work effectively with limited supervision while simultaneously feeling comfortable raising issues to teammates</li>\n<li>Excitement about joining a fast-growing, early-stage company, comfort with a dynamic work environment, and eagerness to take on an evolving range of responsibilities</li>\n<li>Experience working with QA/QC software or Laboratory Information Management Systems (LIMS) to ensure sample traceability and data quality; high comfort level in interfacing with software development teams</li>\n<li>Enjoyment in working closely with people in a wide variety of disciplines and different parts of the world</li>\n<li>Ability to explain technical problems to and collaborate on solutions with domain experts from different disciplines. Comfortable asking questions and requesting help. A strong communicator who enjoys working with colleagues across the company</li>\n</ul>\n<p>It is helpful but not required to have:</p>\n<ul>\n<li>Worked in a small company or as a member of a very small team with a broad mandate working in a fast-paced project environment</li>\n</ul>\n<p>KoBold Metals is an equal opportunity workplace and an affirmative action employer. We are committed to equal employment opportunity for people of any race, color, ancestry, religion, sex, gender identity, sexual orientation, marital status, national origin, age, citizenship, disability, or veteran status.</p>\n<p>Location: Sudbury, Canada. All candidates must be legally authorized to live and work within Canada.</p>\n<p>Compensation: $170,000 - $210,000 CAD</p>\n<p style=\"margin-top:24px;font-size:13px;color:#666;\">XML job scraping automation by <a href=\"https://yubhub.co\">YubHub</a></p>","url":"https://yubhub.co/jobs/job_16971da1-943","directApply":true,"hiringOrganization":{"@type":"Organization","name":"KoBold Metals","sameAs":"https://www.koboldmetals.com/","logo":"https://logos.yubhub.co/koboldmetals.com.png"},"x-apply-url":"https://job-boards.greenhouse.io/koboldmetals/jobs/4677676005","x-work-arrangement":"onsite","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$170,000 - $210,000 CAD","x-skills-required":["Laboratory management","Teamwork","Analytic workflow","Process optimization","Quality assurance/quality control","Equipment maintenance","Stakeholder communication","Geochemical analysis","Sample preparation","Laboratory balances","Microscopes","Spectrometers","Laboratory Information Management Systems (LIMS)"],"x-skills-preferred":[],"datePosted":"2026-04-17T12:39:36.424Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Sudbury Ontario"}},"employmentType":"FULL_TIME","occupationalCategory":"Engineering","industry":"Mining","skills":"Laboratory management, Teamwork, Analytic workflow, Process optimization, Quality assurance/quality control, Equipment maintenance, Stakeholder communication, Geochemical analysis, Sample preparation, Laboratory balances, Microscopes, Spectrometers, Laboratory Information Management Systems (LIMS)","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":170000,"maxValue":210000,"unitText":"YEAR"}}},{"@context":"https://schema.org","@type":"JobPosting","identifier":{"@type":"PropertyValue","name":"YubHub","value":"job_b21858d7-927"},"title":"Senior Software Engineer I","description":"<p>We are seeking a Senior Software Engineer I to help develop software to combat cancer. The ideal candidate will be excited to work as part of an interdisciplinary team of engineers and analysts building end-to-end solutions for our clinical and R&amp;D labs.</p>\n<p>You will be responsible for getting our state-of-the-art lab processes to interface with the rest of our systems. Depending on your skills and our needs, you&#39;ll be working on projects including distributed systems, system integration, database operations, and ETL.</p>\n<p>As a member of a fast-growing team, you’ll take the lead on major projects and collaborate actively with our world-class team of engineers, scientists, designers, and product managers.</p>\n<p>You are passionate about building reliable, maintainable, scalable, and fault-tolerant backend services, and you will have a significant impact on the continued growth of a high-profile technology organization that is changing the landscape on early cancer detection.</p>\n<p>The role reports to our engineering management team. 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The ideal candidate is a seasoned leader who bridges the gap between complex molecular biology and scalable software products in a regulated environment.</p>\n<p>This person is responsible for the technical roadmaps, feature prioritization, software requirements, and specification definition related to Lab Information Management Systems (LIMS), laboratory automation, and software managing sample processing-to-result generation.</p>\n<p>You will define and execute the multi-year technical roadmap for IVD/LDT software platforms, ensuring alignment with clinical needs and regulatory requirements.</p>\n<p>Key responsibilities include:</p>\n<ul>\n<li><p>Leading feature prioritization and software requirements definition of LIMS, lab automation, and software managing the sample processing-to-result generation to optimize high-throughput sample processing and data integrity.</p>\n</li>\n<li><p>Directing the integration of complex diagnostic hardware with cloud-based or on-premise processing software, focusing on seamless end-to-end workflows.</p>\n</li>\n<li><p>Ensuring all software products comply with global regulatory standards, including FDA, CLIA/CAP, ISO 13485, and HIPAA/GDPR data privacy requirements.</p>\n</li>\n<li><p>Collaborating with R&amp;D, Molecular Biology, Clinical Lab, Lab Automation, and Engineering teams to translate complex assay protocols into automated, scalable software requirements.</p>\n</li>\n<li><p>Managing cross-functional dependencies between wet-lab operations, bioinformatics pipelines, and software engineering teams to ensure timely product delivery.</p>\n</li>\n<li><p>Establishing and monitoring key performance indicators (KPIs) for software reliability, processing speed, and diagnostic accuracy in a clinical laboratory environment.</p>\n</li>\n</ul>\n<p>Requirements include:</p>\n<ul>\n<li><p>8+ years in Technical Product Management, with at least 4 years specifically in IVD, Medical Devices, or Clinical SaaS.</p>\n</li>\n<li><p>Proven experience with LIMS/LIS and laboratory automation workflows.</p>\n</li>\n<li><p>Deep familiarity with FDA software guidelines and CLIA regulations.</p>\n</li>\n<li><p>BS/MS in Computer Science, Bioengineering, Molecular Biology, or a related field.</p>\n</li>\n<li><p>Demonstrated experience managing and scaling technical product teams in a regulated environment.</p>\n</li>\n</ul>\n<p>Nice to have qualifications include:</p>\n<ul>\n<li><p>MS or PhD in a technical or scientific field.</p>\n</li>\n<li><p>Experience with Next-Generation Sequencing (NGS) data pipelines.</p>\n</li>\n<li><p>Hands-on experience with cloud infrastructure (AWS/Azure/GCP) in a GxP environment.</p>\n</li>\n</ul>\n<p>The US target range of our base salary for new hires is $220,400 - $281,400. 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This role will enable the development of existing and new capabilities within Lab Operations, take ownership of growing functional areas, and help to support the expansion of lab operations at BigHat. This role reports directly to the Lab Manager.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>inventory incoming and existing materials, track quantities and order more as needed, and restock shelves with necessary materials.</li>\n<li>Respond to purchasing requests from lab users, routing through the appropriate level approval pathways and placing orders for requested items.</li>\n<li>Take leadership of vendor relationships and coordination of support and maintenance services.</li>\n<li>Coordinate, perform, troubleshoot, and document laboratory instrumentation events, communicating updates to the broader team.</li>\n<li>Ensure all projects have the materials and instrumentation necessary to run smoothly.</li>\n<li>Obtain certification for handling, shipping, and disposal of hazardous materials and coordinate shipments and pickups as needed, maintaining good documentation of events.</li>\n<li>Maintain the cleanliness, safety, and organization of the lab and storage spaces.</li>\n<li>Assist with and own documentation of various related areas such as SDS management, SOP writing and processing, and hazardous waste documentation.</li>\n<li>Communicate with lab team members to understand, respond to, and communicate their needs.</li>\n</ul>\n<p>Skills, Knowledge &amp; Expertise:</p>\n<ul>\n<li>BS in Biology, Chemistry, or a related field, with 1+ year(s) of industry experience.</li>\n<li>Experience in a laboratory environment, with experience in lab operations, inventory management, documentation systems, purchasing systems, or instrumentation maintenance a plus.</li>\n<li>Self-motivated individual with attention to detail, excited to work in a dynamic start-up environment.</li>\n<li>Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.</li>\n<li>Excellent record-keeping abilities.</li>\n<li>Experience with Google Suite, with a focus on Google Sheets.</li>\n<li>Experience with LIMS, lab management, and organizational software is a plus.</li>\n</ul>\n<p>Benefits:</p>\n<ul>\n<li>The salary estimated for this position is $80,000 - $105,000 + bonus + options + benefits. 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