Introduction to role

At AstraZeneca, teams work across global boundaries to make an impact and find answers to complex challenges. This role sits at the heart of that mission, combining scientific depth with strategic leadership to advance care in chronic respiratory disease. As US Head of Medical, COPD, this position owns the medical strategy and execution for a novel Interleukin-33 targeting monoclonal antibody, crafting both product and disease area direction across the full lifecycle. Reporting directly to the VP Medical Respiratory, Immunology, Vaccines and Immune Therapies (R&I), this leader will guide a high-performing team, drive launches, and influence how evidence, access and clinical practice come together to transform outcomes for patients living with COPD and severe lower respiratory tract disease. Ready to steer a first-in-class biologic and redefine what’s possible in respiratory medicine?

Accountabilities

• Lead and grow the COPD US medical team, setting clear vision, priorities and standards for excellence in disease area and brand strategy and execution.
• Develop and deliver coordinated medical strategies and plans for COPD and related indications, ensuring alignment with global medical, US commercial and market access partners.
• Develop and implement Transforming Healthcare initiatives that shape the biologics market in COPD, severe LRTD and adjacent areas, using evidence and insight to influence clinical practice and care pathways.
• Own disease area and brand medical budgets and resource planning, ensuring optimal allocation to high-impact activities across the lifecycle.
• Co-lead the COPD Core Value Team with Commercial and Market Access leaders, connecting strategy, science, access and execution to deliver a cohesive launch plan.
• Continuously assess and communicate the competitive landscape, translating insights into differentiated positioning and tactical plans.
• Act as the primary US medical point of contact for the Global Product Team (GPT), providing strategic input on lifecycle management, phase IV strategy and study design.
• Partner with evidence generation teams to define and execute real-world evidence programs that address US clinical, payer and policy needs.
• Build and sustain positive relationships with external authorities, professional societies, patient groups and key internal stakeholders to inform strategy and amplify scientific leadership.
• Serve as a medical spokesperson for COPD in response to media inquiries when required, ensuring accurate, balanced and compliant communication.
• Coach, mentor and develop direct reports, actively leading succession, talent development and engagement within the team.
• Nurture a culture that values scientific rigor, teamwork, innovation and recognition, while maintaining full compliance with AstraZeneca policies and external regulations.

Essential Skills/Experience

• Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
• A Minimum of 7 years of experience in the pharmaceutical industry, ideally in Medical Affairs, working at the country and global/regional level
• Medical/clinical/scientific expertise in Respiratory Disease
• Experienced team leader, with a track record of establishing high performance teams
• Demonstrated track record delivering results in a sophisticated matrix environment, building capabilities, and leading impactful medical initiatives. Experience launching a new product
• US Regulatory Strategy Knowledge including product approval, label requirements/ negotiation
• Consistent track record to collaborate and build internal and external networks
• Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment

Desirable Skills/Experience

• Leadership experience in US Medical Affairs for respiratory biologics or other specialty therapeutics.
• Direct involvement in major US product launches in COPD or related respiratory indications.
• Experience crafting or overseeing real-world evidence programs passionate about payer needs and healthcare system impact.
• Background working closely with field medical teams and external authorities to develop standards of care.
• Track record influencing cross-functional investment decisions using medical insights and data.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an environment where medical leaders sit at the intersection of science and real-world practice, using evidence to influence how care is delivered today and tomorrow. Work alongside experts who embrace change because it sparks innovation, from bold real-world studies to pioneering launches that shift treatment paradigms in respiratory disease. Collaboration across research, medical and commercial functions is embedded in how things get done here, opening doors to new ideas, broader networks and continuous development without borders. Every study designed, every partnership built and every insight translated into practice contributes directly to better outcomes for patients and fuels the next wave of scientific progress.

If this opportunity to lead COPD medical strategy in the US excites you, apply now and take the next step in your career with AstraZeneca.

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About Hebbia

The AI platform for investors and bankers that generates alpha and drives upside.

Founded in 2020 by George Sivulka and backed by Peter Thiel and Andreessen Horowitz, Hebbia powers investment decisions for BlackRock, KKR, Carlyle, Centerview, and 40% of the world's largest asset managers. Our flagship product, Matrix, delivers industry-leading accuracy, speed, and transparency in AI-driven analysis. It is trusted to help manage over $30 trillion in assets globally.

Responsibilities

Apply cutting-edge AI: Develop expertise with leading LLMs (Opus 4.6, GPT-5.2, Gemini 3, etc.), become a SME in Hebbia's product and features, and apply to complex professional settings and workflows

Build domain expertise: Develop an intimate understanding of the complex banking, financial and legal workflows of our users (e.g., credit agreements, lease documents, etc.)

Become a core advisor: Deeply understand our customer stakeholders, drive value and growth as a trusted AI advisor

Drive value-backed growth: Identify and capture value with customers, serving as a key driver of our land-and-expand commercial strategy

Optimize processes for scale: Define and constantly enhance internal processes and workflows to shape the post-sales team and improve our customer experience

Own in ambiguity: Operate with autonomy and clarity in fast-moving, unstructured environments - quickly distill complex problems, learn on the fly, and drive toward actionable solutions across customer and product needs

Requirements

Bachelor's degree, preferably in Finance, Economics, Computer Engineering, or Pre-Law

1-5 years of client-facing experience in top-tier investment banking, institutional investing, corporate law, corporate finance, or consulting roles; relevant internship experience can be considered for recent grads

Strong ownership mindset with a demonstrated track record of outperformance, value creation, and expanded responsibilities

Experience and comfort with leading LLM models and tools; we want to hear about what you've built/tested/researched

Bonus: 5-10 years of client-facing experience with an emphasis on relationship-building

Strong commercial acumen and experience driving revenue expansion, particularly deploying AI/SaaS into enterprise organizations

Technical startup and/or founder experience, building systems and processes for scale

LLM technical knowledge and practical experience implementing into professional workflows

Compensation

The combined base + bonus compensation range (OTE) for this role is $90,000 - $160,000 + competitive equity. The OTE range for those who meet Bonus qualifications is $160,000 - $225,000. These ranges are inclusive of several career levels at Hebbia and will be narrowed during the interview process based on the candidate's experience and qualifications. Adjustments outside of this range may be considered for candidates whose qualifications significantly differ from those outlined in the job description.

Life @ Hebbia

PTO: Unlimited

Insurance: Medical + Dental + Vision + 401K + Wellness Benefits

Eats: Catered lunch daily + doordash dinner credit

Parental leave policy: 3 months non-birthing parent, 4 months for birthing parent

Fertility benefits: $15k lifetime benefit

New hire equity grant: competitive equity package with unmatched upside potential

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