At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.
\nRecognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week.
\nOur head office is purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.
\nAs a Senior Clinical Data Manager II, you will be responsible for coordination of the Clinical Data Management (CDM) deliverables on assigned clinical studies and may be an expert on CDM processes, standards, and technology.
\nYou will coordinate the Clinical Data Management deliverables on assigned studies depending on the relevant model and DM Vendor. Takes accountability and serves as the first line of contact at the study level.
\nDemonstrates leadership and operational knowledge in the planning and delivery of CDM deliverables at a study level potentially under mentorship from a Project Data Manager.
\nCommunicates and collaborates effectively with all study team members. Primary point of contact for DM vendor and provides guidance and supervision to Lead Data Manager/DM Team Lead working on the study (CRO or in-house).
\nOversight of day-to-day operational aspects of CDM for assigned studies; Responsible to identify risks and collaborate with the DM Vendor to mitigate the risk. Escalates issues/risks when necessary.
\nUnderstands corporate, therapeutic/indication or program specific data capture AZ standards.
\nProvide input into CDM related activities associated with regulatory inspections/audits for assigned studies.
\nResponsible for compliance to Trial Master File requirements relating to DM Vendor - Support Senior Leaders to oversee CDM Vendor performance, depending on relevant model. Review, assess and manage DM Vendor delivery against KPIs, budget and overall performance.
\nOversees vendor timelines and milestone deliverables for the assigned studies. Ensures DM Vendor billing is accurate and gives recommendations for payment of invoices.
\nDrive adherence to AZ CDM standards and processes for data quality and consistency of data capturing for assigned studies.
\nDemonstrates willingness to take on ad-hoc activities consistent with current CDM work experience.
\nEnsures relevant training is completed prior to performing tasks.
\nMentoring junior Clinical Data Management colleagues - Performs CDM related ad-hoc requests from Line Manager.
\nEssential Skills/Experience:
\nMinimum of university or college degree in the life sciences or related subject, pharmacy, nursing or equivalent relevant degree
\nMinimum of 5 years of Clinical Data Management and experience in the Biotech/Pharma/CRO industry
\nDemonstrated current understanding of Good Clinical Data Management Practices (GCDMP) and relevant regulatory requirements
\nDemonstrated experience of clinical databases, different clinical data management systems and electronic data capture (EDC)
\nDemonstrate understanding and experience in query management process and reconciliation activities
\nAbility to work flexibly on simultaneous projects and proactively manage time to meet own deadlines.
\nExcellent written and verbal communication skills
\nAbility to work in a global team environment
\nExcellent organizational analytical skills and high attention to detail
\nDesirable Skills/Experience:
\nDemonstrated knowledge of clinical and pharmaceutical drug development process
\nDemonstrated understanding of clinical data system design / development / validation and system interoperability.
\nDemonstrated ability to work effectively with external partners
\nUnderstanding of database structures, programming languages, data standards (CDISC) and practices as they apply to CRF design, database development, data handling and reporting
\nKnowledge of SQL or SAS software
\nExperience leading clinical studies as Data Management Lead
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\nResponsibilities:
\nRequirements:
\nPreferred:
\nBenefits:
\nNote:
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\nLocation
\nSan Francisco
\nEmployment Type
\nFull time
\nDepartment
\nFinance
\nCompensation
\nThe base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If the role is non-exempt, overtime pay will be provided consistent with applicable laws. In addition to the salary range listed above, total compensation also includes generous equity, performance-related bonus(es) for eligible employees, and the following benefits.
\nMore details about our benefits are available to candidates during the hiring process.
\nThis role is at-will and OpenAI reserves the right to modify base pay and other compensation components at any time based on individual performance, team or company results, or market conditions.
\nAbout the Team
\nThe Procurement organization enables our mission by ensuring every dollar is spent responsibly, compliantly, and efficiently. As a key part of this function, the Procurement HelpDesk connects thousands of incoming requests to the right process, stakeholder, or system—delivering a fast, consistent, and compliant experience across Source-to-Contract (S2C), Procure-to-Pay (P2P), Employee Workflows (EWF), and Travel & Expense (T&E). This team is essential to OpenAI’s ability to scale without compromising on compliance or service quality.
\nAbout the Role
\nWe’re looking for a Senior Manager, Procurement HelpDesk to lead the intake and resolution engine for the Procurement function. You’ll own the full lifecycle of request management—from triage logic and intake routing to SLA adherence, stakeholder escalations, and system optimization.
\nThis is a high-impact, execution-focused role that combines operational rigor with program design. You’ll manage centralized intake workflows, resolve or route inbound issues, enforce response SLAs, and maintain intake-to-resolution metrics. You’ll also partner cross-functionally (Legal, Tax, StratFin, Accounting, Security) to ensure escalations are handled quickly and compliantly—and collaborate with engineering to prepare systems for AI-driven support.
\nWhat we’re looking for:
\nA systems-oriented operator who can run a high-volume intake engine with precision, clarity, and speed — while continuously improving how requests flow across the organization.
\nYou likely bring:
\nThis role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees.
\nIn this role, you will:
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