{"version":"0.1","company":{"name":"YubHub","url":"https://yubhub.co","jobsUrl":"https://yubhub.co/jobs/skill/crispr"},"x-facet":{"type":"skill","slug":"crispr","display":"Crispr","count":2},"x-feed-size-limit":100,"x-feed-sort":"enriched_at desc","x-feed-notice":"This feed contains at most 100 jobs (the most recently enriched). For the full corpus, use the paginated /stats/by-facet endpoint or /search.","x-generator":"yubhub-xml-generator","x-rights":"Free to redistribute with attribution: \"Data by YubHub (https://yubhub.co)\"","x-schema":"Each entry in `jobs` follows https://schema.org/JobPosting. YubHub-native raw fields carry `x-` prefix.","jobs":[{"@context":"https://schema.org","@type":"JobPosting","identifier":{"@type":"PropertyValue","name":"YubHub","value":"job_89b1cd26-eed"},"title":"Senior Scientist, Target ID, Immunology Cell Therapy Discovery","description":"<p>We are seeking a dedicated, hands-on Scientist or Senior Scientist to join our Immunology Cell Therapy Discovery team.</p>\n<p>The role centers on novel target identification and validation for cell therapy discovery initiatives, underpinned by an in-depth understanding of cellular and molecular immunology, pathology of inflammation and immune disorders and/or expertise in CAR-T engineering.</p>\n<p>Key responsibilities include: Demonstrating a comprehensive understanding of immunopathology at the cellular and molecular levels; multi-omics and bioinformatic data analysis; the landscape of known drug targets and therapeutics across modalities in clinical use; and emerging targets with investigational therapeutics in the field.</p>\n<p>Partnering with cross-functional teams to initiate and drive discovery efforts focused on immune disorders, ensuring adherence to all relevant laws, regulations, and company policies related to the development and delivery of medicines.</p>\n<p>Initiating cell therapy research,guided by curiosity, hypothesis, and data,to assess and validate novel targets, strategies, and approaches, enabling robust decision-making.</p>\n<p>Essential skills and experience include: Advanced degree in Immunology, virology, innate and adaptive immune response, molecular or cell biology, bioengineering, or a related field; demonstrated proficiency in T- and B-cell culture and functional assays; multicolor flow cytometry (analysis and sorting); bioinformatics; in vivo disease models; and CRISPR and other genome-editing technologies.</p>\n<p>Desirable experience includes a track record of peer-reviewed publications in prestigious immunological journals and/or patents.</p>\n<p style=\"margin-top:24px;font-size:13px;color:#666;\">XML job scraping automation by <a href=\"https://yubhub.co\">YubHub</a></p>","url":"https://yubhub.co/jobs/job_89b1cd26-eed","directApply":true,"hiringOrganization":{"@type":"Organization","name":"Immunology Discovery Group","sameAs":"https://astrazeneca.eightfold.ai","logo":"https://logos.yubhub.co/astrazeneca.eightfold.ai.png"},"x-apply-url":"https://astrazeneca.eightfold.ai/careers/job/563877689867501","x-work-arrangement":"onsite","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$116,284.00 - $174,426.00","x-skills-required":["immunopathology","multi-omics","bioinformatic data analysis","drug targets","investigational therapeutics","cell therapy research","CRISPR","genome-editing technologies"],"x-skills-preferred":["publication record","patent"],"datePosted":"2026-04-18T22:13:46.199Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Waltham, Massachusetts, United States of America"}},"employmentType":"FULL_TIME","occupationalCategory":"Engineering","industry":"Healthcare","skills":"immunopathology, multi-omics, bioinformatic data analysis, drug targets, investigational therapeutics, cell therapy research, CRISPR, genome-editing technologies, publication record, patent","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":116284,"maxValue":174426,"unitText":"YEAR"}}},{"@context":"https://schema.org","@type":"JobPosting","identifier":{"@type":"PropertyValue","name":"YubHub","value":"job_9f76f06c-94e"},"title":"Senior Scientist, Discovery Biology","description":"<p>About Rezo Therapeutics</p>\n<p>Rezo Therapeutics is a biopharma company developing a disease-agnostic, fully-integrated, network biology platform to redefine the understanding of human disease and ability to treat it. Located in San Francisco&#39;s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities.</p>\n<p>The Opportunity</p>\n<p>We are hiring a Senior Scientist, Discovery Biology to join Rezo&#39;s Biology Team. In this role, you will collaborate with an interdisciplinary group combining genetics, proteomics, structural biology, and AI to tackle challenging biological questions and develop transformative therapies.</p>\n<p><strong>Key Responsibilities:</strong></p>\n<ul>\n<li>Develop and optimize molecular and cellular assays to study protein function in 2D/3D tumor models.</li>\n<li>Design and execute CRISPR-based genetic studies to evaluate target function and therapeutic potential.</li>\n<li>Develop and conduct cell-based functional assays to profile small molecule drugs and inform structure-activity relationships (SAR).</li>\n<li>Analyze experimental data, interpret findings, and prepare reports for internal discussions, regulatory filings.</li>\n<li>Collaborate across interdisciplinary teams and effectively communicate scientific results.</li>\n<li>Manage multiple projects efficiently in a dynamic and fast-paced setting.</li>\n</ul>\n<p><strong>Qualifications:</strong></p>\n<ul>\n<li>PhD in cancer biology, or a related field with relevant postdoctoral or industry experience.</li>\n<li>Candidates with a Master’s or Bachelor’s degree with 10-12+ years of expertise, including CRISPR technologies and cancer research, are also encouraged to apply.</li>\n<li>Strong hands-on experience with 2D/3D tumor models and molecular biology techniques.</li>\n<li>Proficiency in genetic manipulation of cancer cells, including CRISPR/Cas9, RNAi, and other genome-editing tools.</li>\n<li>In-depth knowledge of the molecular and cellular mechanisms driving oncogenesis.</li>\n<li>Skilled in performing immunoblotting, proliferation/apoptosis assays, and phenotypic screening assays.</li>\n<li>Proven ability to work independently while fostering collaboration in a team environment.</li>\n<li>Excellent organizational, communication, and interpersonal skills.</li>\n</ul>\n<p><strong>Additional Information</strong></p>\n<p>Compensation at Rezo</p>\n<p>The expected starting salary range for this position based in San Francisco, California for Sr. Scientist is $135,000-$190,000. Actual starting salary will be determined based on multiple job-related factors including candidate’s skills, education, and experience, the level at which they are hired, market demand, business needs, and internal parity.</p>\n<p>Benefits at Rezo</p>\n<p>Medical (HMO or PPO), dental, and vision insurance Discretionary time off policy Company holidays (including summer and winter shutdown) 401(k) retirement savings program Commuter / Mass Transit Benefit Program Healthcare Flexible Spending Account (FSA) Dependent care Flexible Spending Account (FSA) Parental leave Competitive compensation Flexible work schedule</p>\n<p style=\"margin-top:24px;font-size:13px;color:#666;\">XML job scraping automation by <a href=\"https://yubhub.co\">YubHub</a></p>","url":"https://yubhub.co/jobs/job_9f76f06c-94e","directApply":true,"hiringOrganization":{"@type":"Organization","name":"Rezo Therapeutics","sameAs":"https://rezotherapeutics.com/","logo":"https://logos.yubhub.co/rezotherapeutics.com.png"},"x-apply-url":"https://jobs.lever.co/rezotx/5a9ce58e-6c82-40ae-a2ba-7c4f586acc4e","x-work-arrangement":"onsite","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$135,000-$190,000","x-skills-required":["PhD in cancer biology","CRISPR technologies","cancer research","molecular biology techniques","genetic manipulation of cancer cells","genome-editing tools","immunoblotting","proliferation/apoptosis assays","phenotypic screening assays"],"x-skills-preferred":[],"datePosted":"2026-04-17T12:53:30.750Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"San Francisco"}},"employmentType":"FULL_TIME","occupationalCategory":"Engineering","industry":"Healthcare","skills":"PhD in cancer biology, CRISPR technologies, cancer research, molecular biology techniques, genetic manipulation of cancer cells, genome-editing tools, immunoblotting, proliferation/apoptosis assays, phenotypic screening assays","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":135000,"maxValue":190000,"unitText":"YEAR"}}}]}