Scientist, Research Histologist · Boston - Bioscience Team

Wed, 29 Apr 2026 15:07:08 GMT
Research and Development

Boston - Bioscience Team · Waltham, Massachusetts, United States of America · $92,252.00 - $138,378.00 per year · onsite

We are seeking a highly skilled Scientist, Research Histologist to join our team. As a Research Histologist, you will be responsible for performing end-to-end histology processing of tumor and normal tissues from mouse xenograft studies. This includes tissue trimming, paraffin embedding, microtomy, routine histochemical staining, immunohistochemical (IHC) on validated automated staining platforms, and archival of formalin-fixed, paraffin-embedded (FFPE) samples.

You will work collaboratively with in vivo scientists to provide study-aligned histology endpoints. This includes characterizing new tumor models, using IHC-based endpoints with established markers to support pharmacokinetics/pharmacodynamics (PK/PD) and efficacy studies in mouse models following therapeutic drug testing.

In addition to your technical expertise, you will participate in general laboratory maintenance, including buffer preparation, reagent restocking, and basic equipment upkeep. You will also be responsible for data documentation and reports, including digitally archiving slides using the Leica Aperio or similar platform, accessioning FFPE samples into a digital specimen database, and summarizing and presenting findings to project teams.

To be successful in this role, you will require a BS or MS in Biology or a related discipline, with at least 2 years of experience in a histopathology laboratory. You will also need strong organizational skills and attention to detail applied to laboratory responsibilities, data recording, and transparent reporting to project teams.

Desirable skills include experience developing, optimizing, and validating IHC assays, experience using image analysis platforms such as Indica Labs HALO for quantitative analysis of IHC endpoints, and Histotechnician (HT) or Histotechnologist (HTL) (ASCP) certification.