Executive Director, General Manager RMC, Cell Therapy · Global Cell Therapy Manufacturing

Fri, 24 Apr 2026 14:16:16 GMT
Manufacturing

Global Cell Therapy Manufacturing · Rockville, Maryland, United States of America · $300,000 to $315,000 · onsite

If you have the passion and drive to accelerate growth and make people's lives better, then AstraZeneca is the place for you. As a leading biopharmaceutical company, we have a big ambition to deliver more medicines to patients, quicker and more affordably. Our Operations team is accelerating fast, with a clear plan to achieve our Bold Ambition 2030, delivering 20+ new medicines across different modalities.

The Executive Director, General Manager Site Head RMC (Rockville Manufacturing Centre) reports into the Head of Cell Therapy Manufacturing within the Cell Therapy Development and Operations (CTDO) organization. This position is responsible for leading all aspects of autologous Cell Therapy manufacturing for a complex stand-alone manufacturing site, meeting customer requirements and enabling the realisation of the company's operations strategy to scale Cell Therapy manufacturing.

Key responsibilities include:

Leading the RMC Cell Therapy Site for AstraZeneca, the newest cell therapy site

Ensuring processes at the site are carried out in accordance with AstraZeneca's corporate values, Good Manufacturing Practices, Public Health Codes and applicable standards and laws

Achieving critical milestones such as PPQ readiness, pre-license inspection, BLA filing support, commercial launch and scaling

Adopting AI for productivity gains and increasing efficiency in scale

Acting as a role model for the AZ leadership capabilities and setting the standard by which senior employees on the site motivate and empower staff to deliver outstanding performance and customer service

Ensuring that the site's products are made available to external customers while adhering to regulations, quality standards, budget and policies

Setting annual objectives in line with CTDO scorecards, measuring the achievement of those individual targets and taking remedial actions where required

Championing the design of appropriate methods for improving productivity, quality and SHE standards and overseeing the implementation of these across the site

Inspiring staff to coach and develop talent to ensure a healthy talent pipeline and succession for senior positions

Creating an environment in which the working teams can make independent decisions to mitigate any risks to the patient and/or business reputation

Building and maintaining good reputation and community relations with external stakeholders

Approximate number of people managed: 8-9 direct reports across site supply chain, manufacturing, lean digital, human resources and dotted line MSAT, finance, IT and Quality. In total (all levels): 500-1000.

Preferred Requirements:

University graduate, with significant experience (10+ years) in the field of Manufacturing, & Supply Chain; People Management and people development

Proven track record in managing and leading a large, high-performing team with preferred expertise in autologous CAR-T cell therapies or biologics in a clinical and commercial manufacturing environment

Ability to engage people in change and working with uncertainty and ambiguity

Key skills and competencies:

Site experience: 10+ years in manufacturing, engineering, facilities, and/or quality site leadership

Team leadership: Leads a multidisciplinary site leadership team and builds high-performing talent benches

Regulatory, quality, and SHE governance: Demonstrated oversight ensuring compliance with all applicable standards

Strategic thinking, influence, and stakeholder management: Translates enterprise strategy into site priorities; influences global and functional stakeholders with credibility and gravitas

Risk-based decision making: Makes timely, compliant, risk-informed decisions at the site level

Digital and AI stewardship: Adopts and embeds digital and AI-enabled tools to improve site performance

Operational execution leadership: Drives OpEx and Lean execution with clear milestones, resource plans, and performance metrics

Join us in our unique and ambitious world, where we balance the expectation of being in the office while respecting individual flexibility. We work five days per week as a site leader/general manager, but that doesn't mean we're not flexible.

Annual base salary for this position ranges from $300,000 to $315,000. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related experience.