<?xml version="1.0" encoding="UTF-8"?>
<source>
  <jobs>
    <job>
      <externalid>26909f66-57c</externalid>
      <title>Sr. Director, Clinical Operations</title>
      <description><![CDATA[<p>Metaphore Biotechnologies is seeking a Senior Director of Clinical Operations to lead the hands-on execution of early clinical development activities for the company’s first-in-human program.</p>
<p>The successful candidate will be highly operational, able to ramp quickly, and comfortable establishing fit-for-purpose capabilities while working across internal teams, external partners, and consultants to move studies forward with urgency and rigor.</p>
<p>Key Responsibilities:</p>
<ul>
<li>Lead clinical operations planning and execution for early development programs, with primary accountability for first-in-human study readiness, global start-up, and delivery against key milestones.</li>
<li>Develop and maintain integrated study plans, timelines, budgets, forecasts, resource requirements, and risk-mitigation strategies aligned with clinical and corporate objectives.</li>
<li>Lead CRO and vendor selection and oversight, including requests for proposals, bid evaluations, scope-of-work development, budget negotiations, change-order management, performance monitoring, and issue escalation.</li>
<li>Partner with Clinical Development and Medical leadership to evaluate protocols, study designs, operational feasibility, and start-up requirements.</li>
<li>Represent Clinical Operations on cross-functional study and program teams, partnering with other relevant functions internally and externally.</li>
<li>Develop and execute the Phase 1 site strategy, including the identification, qualification, activation, and ongoing management of sites with appropriate participant access, clinical pharmacology capabilities, bioanalytical infrastructure, and operational experience.</li>
<li>Lead global clinical operations activities across the U.S., Europe, Australia, and other ex-U.S. regions, accounting for applicable regulatory, ethics, site, laboratory, vendor, and country-specific start-up requirements.</li>
<li>Contribute to operational planning for potential studies in China and coordinate with internal and external experts to support regional requirements.</li>
<li>Establish an effective operating cadence with CROs, sites, vendors, consultants, and functional partners to track deliverables, timelines, budgets, quality metrics, risks, and escalation paths.</li>
<li>Oversee the development and maintenance of study-level operational documentation, including monitoring, communication, enrollment, vendor-oversight, and risk-management plans.</li>
<li>Partner with CMC and clinical supply stakeholders to support investigational product packaging, labeling, distribution, accountability, and site readiness.</li>
<li>Ensure clinical studies are conducted in accordance with the protocol, ICH-GCP, applicable regulatory requirements, internal procedures, and established quality standards.</li>
<li>Maintain inspection-ready clinical trial documentation and oversee the completeness, quality, and timeliness of the Trial Master File.</li>
<li>Identify operational risks early and implement mitigation and contingency plans related to timelines, sites, enrollment, vendors, clinical supply, and data delivery.</li>
<li>Establish scalable, fit-for-purpose clinical operations processes, systems, SOPs, and governance practices appropriate for a growing biotechnology company.</li>
<li>Provide clear and timely updates on study status, timelines, budgets, risks, and mitigation plans to the CMO, clinical leadership, and other key stakeholders.</li>
</ul>
<p>Required Qualifications:</p>
<ul>
<li>BS/MS/PhD degree in a scientific, healthcare, or related discipline; an advanced degree is preferred.</li>
<li>10+ years of progressive clinical operations experience in the biotechnology or pharmaceutical industry.</li>
<li>Direct experience leading first-in-human or Phase 1 studies from operational planning and vendor selection through regulatory and ethics submissions, site activation, first-participant-in, and ongoing execution.</li>
<li>Strong working knowledge of CRO and vendor selection and oversight, site strategy, global study start-up, and operational planning.</li>
<li>Demonstrated experience managing study budgets, vendor contracts, scopes of work, change orders, timelines, and forecasts.</li>
<li>Experience reviewing clinical protocols and translating study designs into executable operational plans.</li>
<li>Experience supporting clinical pharmacology/DMPK, including dose-escalation, SAD/MAD, biomarker, or other early-phase study designs, as applicable.</li>
<li>Experience conducting studies involving healthy volunteers or specific patient populations.</li>
<li>Broad understanding of FDA, EU, and other ex-U.S. clinical trial requirements.</li>
<li>Strong knowledge of ICH-GCP, sponsor oversight responsibilities, TMF requirements, clinical quality standards, and inspection readiness.</li>
<li>Ability to operate independently and influence without direct authority in a fast-paced environment with limited infrastructure and high levels of ambiguity.</li>
<li>Strong communication and cross-functional collaboration skills, with the ability to manage internal stakeholders, external vendors, and consultants effectively.</li>
<li>Ability and willingness to travel domestically and internationally, as needed.</li>
</ul>
<p>Preferred Qualifications:</p>
<ul>
<li>Experience in both biotechnology and pharmaceutical company environments, with exposure to the broader clinical development lifecycle.</li>
<li>Direct experience initiating and executing early-phase studies in Australia, including familiarity with local regulatory, ethics, site, and vendor pathways.</li>
<li>Experience with China regulatory and clinical operations pathways.</li>
<li>Experience in antibody therapeutics, biologics, or other advanced therapeutic development programs.</li>
<li>Experience operationalizing biomarker, immunogenicity, pharmacokinetic, pharmacodynamic, or other specialized sample-collection and bioanalytical strategies within early-phase studies.</li>
<li>Experience establishing clinical operations infrastructure, processes, systems, and external partnerships within an organization entering the clinic for the first time.</li>
</ul>
<p>The salary range for this role is $213,000 - $280,000. Metaphore Biotechnologies, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.</p>
<p style="margin-top:24px;font-size:13px;color:#666;">Job Data by <a href="https://yubhub.co">YubHub</a>.</p>]]></description>
      <jobtype>full-time</jobtype>
      <experiencelevel>senior</experiencelevel>
      <workarrangement></workarrangement>
      <salaryrange>$213,000 - $280,000</salaryrange>
      <skills>clinical operations, CRO management, vendor management, study planning, ICH-GCP, regulatory compliance, communication, collaboration, biotechnology, pharmaceutical industry, antibody therapeutics, biologics, biomarker, immunogenicity, pharmacokinetic, pharmacodynamic</skills>
      <category>Healthcare</category>
      <industry>Healthcare</industry>
      <employername>Metaphore Biotechnologies, Inc.</employername>
      <employerlogo>https://logos.yubhub.co/flagshippioneeringinc.com.png</employerlogo>
      <employerdescription>Metaphore Biotechnologies, Inc. is a privately held biotechnology company building the next generation of biological therapeutics.</employerdescription>
      <employerwebsite>https://flagshippioneeringinc.com</employerwebsite>
      <compensationcurrency>USD</compensationcurrency>
      <compensationmin>213000</compensationmin>
      <compensationmax>280000</compensationmax>
      <compensationinterval>yearly</compensationinterval>
      <applyto>https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8830615002</applyto>
      <location>Somerville, MA</location>
      <city>Somerville</city>
      <state>MA</state>
      <postalcode></postalcode>
      <country>US</country>
      <postedate>2026-10-27</postedate>
    </job>
    <job>
      <externalid>a67368f7-0dc</externalid>
      <title>Senior / Principal Computational Biologist</title>
      <description><![CDATA[<p>Join Cellarity, a rapidly growing biotech company, as a Senior / Principal Computational Biologist. You will play a critical role in bringing new medicines to patients by applying your skills to real-world therapeutic challenges. As a computational biology lead, you will collaborate with cross-functional teams to co-develop hypotheses from cell atlases and advance programs from biological model development through hit identification and lead optimization.</p>
<p>Responsibilities:</p>
<ul>
<li>Act as the CompBio lead and core team representative on cross-functional drug programs</li>
<li>Develop and lead data analysis strategies and ideation across diverse projects</li>
<li>Apply computational biology and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets</li>
<li>Use transcriptomic data to develop disease hypotheses, evaluate models, analyze perturbation effects, and validate hits and leads</li>
<li>Work with experimental scientists to ensure study designs and data deliver high-value readouts and actionable insights</li>
<li>Contribute to internal AI agent development for Cellarity&#39;s scientific use cases</li>
</ul>
<p>Requirements:</p>
<ul>
<li>Ph.D. or equivalent in biology, computational biology, or related scientific field</li>
<li>3+ years of relevant industry experience</li>
<li>Extensive experience in analyzing and deriving hypotheses from single-cell and bulk transcriptomic data</li>
<li>Demonstrated understanding of molecular and systems biology, diverse molecular data types, and analysis tools</li>
<li>Practical programming and scripting skills, preferably in Python</li>
<li>Fluency with AI tools to accelerate daily scientific work</li>
</ul>
<p>Nice to Have:</p>
<ul>
<li>Background in metabolic or liver diseases, autoimmune disease, or hematology</li>
<li>Experience with generating, analyzing, and deriving hypotheses from other single-cell omics data types or large-scale clinical datasets</li>
<li>Experience driving an impactful and relevant project within industry</li>
<li>Background in statistics or machine learning</li>
</ul>
<p>Benefits:</p>
<ul>
<li>Healthcare coverage</li>
<li>Annual incentive program</li>
<li>Retirement benefits</li>
<li>Broad range of other benefits</li>
</ul>
<p style="margin-top:24px;font-size:13px;color:#666;">Job Data by <a href="https://yubhub.co">YubHub</a>.</p>]]></description>
      <jobtype>full-time</jobtype>
      <experiencelevel>senior</experiencelevel>
      <workarrangement></workarrangement>
      <salaryrange>$179,000 - $236,000</salaryrange>
      <skills>Python, computational biology, machine learning, single-cell omics, transcriptomic data analysis, metabolic diseases, liver diseases, autoimmune disease, hematology, statistics, clinical data analysis</skills>
      <category>Research</category>
      <industry>Healthcare</industry>
      <employername>Cellarity</employername>
      <employerlogo>https://logos.yubhub.co/flagshippioneeringinc.com.png</employerlogo>
      <employerdescription>Cellarity is a biotech company that aims to redesign the way drugs are created by focusing on cellular dysfunction rather than a single target.</employerdescription>
      <employerwebsite>https://flagshippioneeringinc.com</employerwebsite>
      <compensationcurrency>USD</compensationcurrency>
      <compensationmin>179000</compensationmin>
      <compensationmax>236000</compensationmax>
      <compensationinterval>yearly</compensationinterval>
      <applyto>https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8742220002</applyto>
      <location>Somerville, MA</location>
      <city>Somerville</city>
      <state>MA</state>
      <postalcode></postalcode>
      <country>US</country>
      <postedate>2026-10-27</postedate>
    </job>
    <job>
      <externalid>5fb357ab-204</externalid>
      <title>Musketeer - On Premise Specialist</title>
      <description><![CDATA[<p>We are seeking a Musketeer - On Premise Specialist to join our team in Somerville, Massachusetts.</p>
<p>At Red Bull, there&#39;s no such thing as a typical sales rep,we live, work, and breathe the job. As a Musketeer, you will be the personification of the brand in Red Bull&#39;s On Premise business.</p>
<p><strong>Responsibilities:</strong></p>
<ul>
<li>RED BULL AMBASSADOR: Showcase our premium brand through your unique personality, bringing it to life in trendy restaurants and bars, clubs, festivals, and exclusive events. Establish and nurture relationships with key influencers and business partners.</li>
<li>CITY ENTREPRENEUR: Take full responsibility for On Premise sales and marketing activities in your market, developing and deploying ingenious strategies and innovative tools to deliver the perfect pitch for Red Bull.</li>
<li>INDISPENSABLE BUSINESS CONSULTANT: Strengthen and nurture long-term professional relationships with established customers, creating new alliances with key influencers and industry experts. Utilize your sales and negotiation skills to achieve mutually beneficial increases in earnings.</li>
</ul>
<p><strong>Requirements:</strong></p>
<ul>
<li>Established contacts within the industry, or the ability and desire to make them quickly and smoothly</li>
<li>Experience in the beverage industry, gastronomy, hospitality and catering, marketing, sales, or as your own boss is highly preferred</li>
<li>Strong ability to navigate the technical landscape of iPhones and iPads, various custom applications, and programs such as Word, Excel, and PowerPoint</li>
<li>Able to work flexible hours, evenings, weekends, and some holidays, and thrive on autonomy</li>
<li>Excellent written and verbal communication skills</li>
<li>Strong understanding of sales processes and ability to analyze sales and customer data</li>
<li>Must be at least 21 years of age</li>
<li>Bachelor&#39;s degree preferred</li>
<li>Fluent in English, additional language skills an advantage</li>
</ul>
<p><strong>Benefits:</strong></p>
<ul>
<li>Comprehensive Medical, Dental and Vision Plans</li>
<li>401k Match</li>
<li>Family Leave</li>
<li>PTO &amp; Paid Holiday Schedule</li>
<li>Pet, Legal, and Life Insurance</li>
<li>Tuition Reimbursement</li>
</ul>
<p><strong>Salary:</strong> $69,000 - $103,500 + cash incentives</p>
<p style="margin-top:24px;font-size:13px;color:#666;">Job Data by <a href="https://yubhub.co">YubHub</a>.</p>]]></description>
      <jobtype>full-time</jobtype>
      <experiencelevel>senior</experiencelevel>
      <workarrangement>onsite</workarrangement>
      <salaryrange>$69,000 - $103,500</salaryrange>
      <skills>sales, marketing, communication, analysis, negotiation, beverage industry, gastronomy, hospitality, catering, management</skills>
      <category>Sales</category>
      <industry>Beverage</industry>
      <employername>Red Bull</employername>
      <employerlogo>https://logos.yubhub.co/jobs.redbull.com.png</employerlogo>
      <employerdescription>Red Bull is a global energy drink company.</employerdescription>
      <employerwebsite>https://jobs.redbull.com</employerwebsite>
      <compensationcurrency>USD</compensationcurrency>
      <compensationmin>69000</compensationmin>
      <compensationmax>103500</compensationmax>
      <compensationinterval>yearly</compensationinterval>
      <applyto>https://jobs.redbull.com/us-en/musketeer-on-premise-specialist-ref34287n</applyto>
      <location>Somerville, Massachusetts</location>
      <city>Somerville</city>
      <state>Massachusetts</state>
      <postalcode></postalcode>
      <country></country>
      <postedate>2026-09-26</postedate>
    </job>
    <job>
      <externalid>54b9c175-e9e</externalid>
      <title>Physical Therapist Assistant</title>
      <description><![CDATA[<p>Are you a Physical Therapist Assistant looking to thrive in a supportive, balanced environment? Join ATI, a leader in Outpatient Physical Therapy, where you&#39;ll be part of a team redefining musculoskeletal (MSK) care. With a mission to deliver exceptional patient outcomes and empower clinicians to succeed, we provide the resources and opportunities to help you grow professionally and personally.</p>
<p><strong>Why Choose ATI?</strong></p>
<p>At ATI, you join a team at the forefront of MSK care, with a strong track record of outcomes, reputation, and growth opportunities.</p>
<ul>
<li>Award-Winning Outcomes: Recognised five years in a row in the Merit-Based Incentive Payment System (MIPS), with a 90% patient satisfaction rate and a 74% Net Promoter Score.</li>
<li>Outstanding Reputation: Our clinics average a 4.9 / 5 Google Review rating across locations, reflecting our commitment to exceptional care and patient experience.</li>
<li>Certified Expertise: More than a decade of ABPTRFE-accredited Sports and Orthopedic Residencies (with a 96%+ first-time exam pass rate), plus an Upper Extremity Athlete Fellowship with graduates serving across collegiate and professional sports.</li>
<li>Research Leadership: Our partnering nonprofit, the Institute for Musculoskeletal Advancement (iMSKA), contributes to the field with 10–15 published papers and 30+ scientific presentations each year.</li>
<li>Community Impact: Through the ATI Foundation, we support individuals with physical disabilities in the communities we serve.</li>
</ul>
<p><strong>Clinician Support and Development</strong></p>
<p>At ATI, we prioritise your growth, your well-being, and your ability to focus on patients.</p>
<ul>
<li>Collaborative Care: Work alongside various specialties with manageable caseloads.</li>
<li>Ongoing Learning: Access structured mentorship, residency programs, and leadership training.</li>
<li>Comprehensive CEU Support: Take advantage of an external CEU benefit and 100&#39;s of live and on-demand development sessions to stay at the forefront of evidence-based care.</li>
</ul>
<p><strong>Benefits Highlights</strong></p>
<p>We offer a competitive compensation package with an incentive plan, and comprehensive benefits, including:</p>
<ul>
<li>Paid Time Off: Generous PTO, holiday pay, CEU, and &#39;Be Well Days&#39; to recharge, prioritise mental and physical health.</li>
<li>Medical, Dental &amp; Vision Coverage: Flexible plan options.</li>
<li>401(k) Match: Competitive employer matching.</li>
<li>Childcare Tuition Assistance: Discounted rates.</li>
<li>Health Savings &amp; Flexible Spending Accounts: Tax-saving options.</li>
<li>Short- &amp; Long-Term Disability: 100% employer-paid income protection plans.</li>
<li>Life Insurance: Employer-paid and voluntary options.</li>
<li>Parental Leave &amp; Adoption Assistance: Paid time for new parents and support for adoption costs.</li>
<li>Wellness Programs: Including weight-loss and lifestyle coaching, digital mental-health support, and 24/7 virtual telehealth access.</li>
<li>Corporate Discounts: Exclusive deals for employees.</li>
</ul>
<p><strong>Responsibilities</strong></p>
<p>You will be empowered to make a difference for your patients: provide direct patient care and physical therapy treatments under the supervision of a Physical Therapist, while fostering a strong relationship with each patient to help them achieve their functional goals.</p>
<p><strong>Qualifications</strong></p>
<ul>
<li>Degree from an accredited Physical Therapy Assistant Program.</li>
<li>Current professional licensure as a Physical Therapist Assistant or license eligible based on the rules and regulations of the state in which you are applying for role.</li>
</ul>
<p>The salary range for this position is $30-$39 per hour.</p>
<p style="margin-top:24px;font-size:13px;color:#666;">Job Data by <a href="https://yubhub.co">YubHub</a>.</p>]]></description>
      <jobtype>full-time</jobtype>
      <experiencelevel></experiencelevel>
      <workarrangement></workarrangement>
      <salaryrange>$30-$39 per hour</salaryrange>
      <skills>Physical Therapy Assistant, Patient Care, Physical Therapy Treatments</skills>
      <category>Healthcare</category>
      <industry>Healthcare</industry>
      <employername>ATI</employername>
      <employerlogo>https://logos.yubhub.co/careers.atipt.com.png</employerlogo>
      <employerdescription>ATI is a leader in Outpatient Physical Therapy with a mission to deliver exceptional patient outcomes and empower clinicians to succeed.</employerdescription>
      <employerwebsite>https://careers.atipt.com</employerwebsite>
      <compensationcurrency>USD</compensationcurrency>
      <compensationmin>30</compensationmin>
      <compensationmax>39</compensationmax>
      <compensationinterval>hourly</compensationinterval>
      <applyto>https://careers.atipt.com/somerville-ma/physical-therapist-assistant/8BEE9F8008054E6FB479294E1C00AC21/job/</applyto>
      <location>Somerville, MA</location>
      <city>Somerville</city>
      <state>MA</state>
      <postalcode>02143</postalcode>
      <country>US</country>
      <postedate>2026-06-22</postedate>
    </job>
    <job>
      <externalid>715cd032-22c</externalid>
      <title>Physical Therapist</title>
      <description><![CDATA[<p>Are you a Physical Therapist looking to thrive in a supportive, balanced environment? Join ATI, a leader in Outpatient Physical Therapy, where you’ll be part of a team redefining musculoskeletal (MSK) care. With a mission to deliver exceptional patient outcomes and empower clinicians to succeed, we provide the resources and opportunities to help you grow professionally and personally. You will earn a salary ranging from $85K to $105K annually.</p>
<p><strong>Why Choose ATI?</strong></p>
<p>At ATI, you join a team at the forefront of MSK care, with a strong track record of outcomes, reputation, and growth opportunities.</p>
<ul>
<li>Award-Winning Outcomes: Recognised five years in a row in the Merit-Based Incentive Payment System (MIPS), with a 90% patient satisfaction rate and a 74% Net Promoter Score.</li>
<li>Outstanding Reputation: Our clinics average a 4.9 / 5 Google Review rating across locations, reflecting our commitment to exceptional care and patient experience.</li>
<li>Certified Expertise: More than a decade of ABPTRFE-accredited Sports and Orthopedic Residencies (with a 96%+ first-time exam pass rate), plus an Upper Extremity Athlete Fellowship with graduates serving across collegiate and professional sports.</li>
<li>Research Leadership: Our partnering nonprofit, the Institute for Musculoskeletal Advancement (iMSKA), contributes to the field with 10–15 published papers and 30+ scientific presentations each year.</li>
<li>Community Impact: Through the ATI Foundation, we support individuals with physical disabilities in the communities we serve.</li>
</ul>
<p><strong>Clinician Support and Development</strong></p>
<p>At ATI, we prioritise your growth, your well-being, and your ability to focus on patients.</p>
<ul>
<li>Collaborative Care: Work alongside various specialties with manageable caseloads.</li>
<li>Ongoing Learning: Access structured mentorship, residency programs, and leadership training.</li>
<li>Comprehensive CEU Support: Take advantage of an external CEU benefit and hundreds of live and on-demand development sessions to stay at the forefront of evidence-based care.</li>
</ul>
<p><strong>Benefits Highlights</strong></p>
<p>We offer a competitive compensation package with an incentive plan, and comprehensive benefits, including:</p>
<ul>
<li>Paid Time Off: Generous PTO, holiday pay, CEU, and “Be Well Days” to recharge, prioritise mental and physical health.</li>
<li>Medical, Dental &amp; Vision Coverage: Flexible plan options.</li>
<li>401(k) Match: Competitive employer matching.</li>
<li>Loan Reimbursement: Up to $25,000 in select markets.</li>
<li>Childcare Tuition Assistance: Discounted rates.</li>
<li>Health Savings &amp; Flexible Spending Accounts: Tax-saving options.</li>
<li>Short- &amp; Long-Term Disability: 100% employer-paid income protection plans.</li>
<li>Life Insurance: Employer-paid and voluntary options.</li>
<li>Parental Leave &amp; Adoption Assistance: Paid time for new parents and support for adoption costs.</li>
<li>Wellness Programs: Including weight-loss and lifestyle coaching, digital mental-health support, and 24/7 virtual telehealth access.</li>
<li>Corporate Discounts: Exclusive deals for employees.</li>
</ul>
<p><strong>Responsibilities</strong></p>
<p>You will be empowered to make a difference for your patients: performing detailed assessments, creating tailored treatment plans, and working side-by-side with a team of healthcare experts to deliver care that’s truly patient-centred.</p>
<p><strong>Qualifications</strong></p>
<ul>
<li>Degree from an accredited Physical Therapy Program</li>
<li>Current professional licensure as a Physical Therapist or license eligible based on the rules and regulations of the state in which you are applying for role</li>
</ul>
<p style="margin-top:24px;font-size:13px;color:#666;">Job Data by <a href="https://yubhub.co">YubHub</a>.</p>]]></description>
      <jobtype>full-time</jobtype>
      <experiencelevel></experiencelevel>
      <workarrangement></workarrangement>
      <salaryrange>$85K-$105K annually</salaryrange>
      <skills>Physical Therapy, Musculoskeletal care, Patient assessment, Treatment planning</skills>
      <category>Healthcare</category>
      <industry>Healthcare</industry>
      <employername>ATI</employername>
      <employerlogo>https://logos.yubhub.co/careers.atipt.com.png</employerlogo>
      <employerdescription>ATI is a leader in Outpatient Physical Therapy, delivering exceptional patient outcomes and empowering clinicians to succeed.</employerdescription>
      <employerwebsite>https://careers.atipt.com</employerwebsite>
      <compensationcurrency>USD</compensationcurrency>
      <compensationmin>85000</compensationmin>
      <compensationmax>105000</compensationmax>
      <compensationinterval>yearly</compensationinterval>
      <applyto>https://careers.atipt.com/somerville-ma/physical-therapist/4C32B43A2A524562950F1E8489BA1385/job/</applyto>
      <location>Somerville, MA</location>
      <city>Somerville</city>
      <state>MA</state>
      <postalcode>02143</postalcode>
      <country>US</country>
      <postedate>2026-06-22</postedate>
    </job>
  </jobs>
</source>