Reporting to the Head of Clinical Diagnostics, you will drive novel, high-throughput ligand binding assay (LBA) strategies outside of conventional plate-based assays,focusing heavily on automation, speed, and high precision.

You will lead a high-performing team developing and maintaining immunodiagnostic assays to support vaccine clinical trials and epidemiological studies.

Key Responsibilities

Strategy and Innovation

• Envision and execute next-generation ligand binding assay (LBA) strategies, driving high-throughput, automated, and rapid-completion alternatives to traditional plate-based assays.
• Keep abreast of scientific and technological breakthroughs; identify and in-license/in-house promising new diagnostic platforms.

Project and Clinical Leadership

• Set objectives for and manage multiple assay development projects (serological, immunodiagnostic, and toxicological).
• Drive the prioritization of clinical epidemiological studies by optimizing logistical testing resources.
• Author and review high-level technical documents, validations, regulatory responses, and scientific publications.

Collaboration and Influence

• Collaborate across internal Vaccines R&D teams and external partners to integrate cutting-edge testing technologies into clinical strategies.
• Lead technology transfers and represent the department in key scientific and strategic discussions.

People Management and Compliance

• Direct and mentor a diverse team of scientists, including direct management of multiple subordinate managers.
• Ensure all laboratory work and clinical testing strictly adhere to Pfizer values, SOPs, and GCLP/cGMP standards.

Minimum Qualifications

Education and Experience

• PhD in Immunology or a closely related biological field.
• 5+ years of industry experience leading the development of advanced tools and assays and the implementation of cutting edge technologies.
• Experience managing other managers and mentoring junior scientists.

Technical Expertise

• Deep expertise in assay development and lifecycle management (from concept/design to long-term sustainability).
• Strong background in robotic sample handling systems, clinical batching, Design of Experiments (DoE), and general biostatistical analysis.
• Expert knowledge of analytical/clinical validations under GCLP and/or cGMP guidelines.

Tools and Technology

• Proficiency with LIMS, DoE software, and standard enterprise suites.

Communication and Influence

• Strong publication record (primary author) and experience presenting concise, high-level data to senior leadership.

Preferred Qualifications

• Experience leveraging AI, machine learning, or advanced algorithmic scheduling software to optimize high-throughput laboratory automation and automated assay data analysis pipelines.
• Experience interacting with/responding to regulatory agencies.

Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.

Physical/Mental Requirements Sitting of long periods of time and occasional walking from one building to another.

Salary Information The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program.

Job Data by YubHub.

The successful candidate will lead the group, provide strategic, innovative scientific and technical leadership for upstream and downstream bioprocess development supporting diverse vaccines portfolio.

This role is part of a cross-functional team focused on polysaccharide fermentation and purification process development for carbohydrate- and other modality-based conjugate vaccines.

Responsibilities:

• Lead and develop a high-performing team of upstream and downstream process development scientists and engineers, drive the vaccines program, while setting scientific direction, establishing priorities, building technical capability, and ensuring high standards for rigor, quality, and accountability.
• Drive development of robust, scalable, and transferable manufacturing processes.
• Provide strategic leadership, serve as a strategic scientific owner for vaccine programs by defining process development strategy, aligning technical plans with program objectives, and ensuring decisions are informed by scientific evidence, manufacturability, timelines, and regulatory expectations.
• Collaborate closely with colleagues across EBPD, Vaccines, BTxPS, and PGS organizations to support integrated process development and product advancement.
• Partner with cross-functional projects team, provide project updates, technical strategies, risks, propose mitigation plans, communicate trade-offs, and drive alignment among all stakeholders.
• Lead technology transfer strategy for developed processes to internal and external clinical manufacturing sites, including preparation and review of process descriptions, technical packages, risk assessments, process control rationale, and troubleshooting plans.
• Foster innovation through adoption of emerging bioprocess technologies, automation, digital tools, and data-driven approaches that enhance process efficiency, product quality, scalability, and robustness.
• Continuously evaluate process performance, equipment capabilities, and experimental workflows to identify gaps, mitigate risks, and propose practical improvements.
• Mentor and develop scientific talent while building organizational capability and succession strength.

Requirements:

• PhD in Chemical Engineering, Biochemical Engineering, Bioengineering, Microbiology, Biochemistry, or a related discipline, with a minimum of 8 years of relevant experience.
• Demonstrated expertise in vaccine process development, preferably for capsular or exopolysaccharides, conjugate vaccines, bacterial antigens, carrier proteins, or other microbial-based vaccine platforms.
• Hands-on technical depth in microbial fermentation and developing polysaccharide recovery and purification processes.
• Strong knowledge of polysaccharide critical quality attributes, in-process controls, design of experiments, scale-down model development, and process characterization.
• Demonstrated ability to collaborate effectively across cross-functional teams, including process development, analytical, formulation, quality, regulatory, and manufacturing groups, to advance complex vaccine development programs.
• Ability to drive projects, translate scientific strategies into executable development plans, manage competing priorities, and guide teams through ambiguity while maintaining accountability for program deliverables.
• Experience authoring and reviewing development reports, process descriptions, technology-transfer packages, risk assessments, and CMC content, with practical understanding of quality-by-design principles, data integrity, and phase-appropriate regulatory expectations for clinical manufacturing.
• Excellent organizational, interpersonal, and communication skills to effectively influence and collaborate in a fast-paced, multi-disciplinary team environment.

Benefits:

• Comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.
• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holiday and personal days.
• Paid caregiver/parental and medical leave.
• Health benefits to include medical, prescription drug, dental and vision coverage.

Job Data by YubHub.

Operating at the intersection of scientific fluency, design excellence, data-driven space planning, and stakeholder engagement, the role partners with R&D leaders and scientists to program, plan, and continuously optimize laboratory environments that are safe, flexible, efficient, and purpose-built for the science they support.

Responsibilities:

• Scientific requirements translation & lab space programming , Execute engagement with R&D leaders and scientists to understand current and future portfolio-wide scientific requirements and translate them into practical laboratory, support, and associated office-space solutions.
• Ownership & evolution of global laboratory design standards , Own and maintain Pfizer's laboratory planning and design standards , across laboratories, hybrid workspaces, and shared support functions , driving their evolution and keeping them current and shared with the COE.
• Flexible, adaptable & colleague-centered design , Identify opportunities for flexible, adaptable laboratory design as science priorities evolve, applying metrics and standards while customizing for colleague needs and intended use.
• Master planning, demand forecasting & utilization analytics , Support site, campus, and network master planning and strategic portfolio planning , forecasting laboratory and workplace demand; providing capacity, utilization, and feasibility analysis; and evaluating renovation, consolidation, expansion, and new-build options and their tradeoffs.
• Cross-functional stakeholder liaison , Serve as the primary liaison among scientists, project teams, architects, engineers, and planners for lab space design and planning initiatives, and as the team's liaison to DCM and the Sustainability & Hospitality COE.
• Design & construction project delivery , Develop project scopes and support design and construction teams (internal staff and external architects, engineers, and construction managers) through design, construction, commissioning, start-up, and occupancy.
• Small-project management & construction oversight , Manage multiple concurrent small projects (typically under $50K) on time, on budget, and safely , covering feasibility and test fits, proposals, logistics, work orders, Job Hazard Analysis (JHA), construction oversight, and multi-trade coordination , and manage approved budgets (purchase orders, Ariba, Statements of Work).
• Innovation, sustainability & change management , Bring innovative practices that keep Pfizer ahead of workplace-design and change-management trends, and embed sustainability, resilience, and operational continuity , energy efficiency, waste reduction, eco-friendly materials, and colleague well-being , into laboratory recommendations.

Requirements:

• Bachelor's degree in Architecture, Interior Design, Engineering, a scientific discipline, or a related built-environment field (equivalent professional qualification or experience accepted in lieu).
• 7+ years of progressive experience in laboratory design & planning, space planning, or workplace/occupancy planning, including programming and design across multiple project phases and facility types.
• Demonstrated expertise in pharmaceutical or biotechnology research environments and specialized laboratory types (e.g., biology, chemistry, analytical and pharmaceutical sciences, process development, vivarium, clean room, containment), including the scientific equipment, workflows, and operational, safety, and regulatory (e.g., cGMP) considerations that shape laboratory design.
• Proficiency with AutoCAD and Autodesk Construction Cloud (ACC); working knowledge of CAFM / IWMS and space-management platforms (e.g., TRIRIGA); and proficiency with Microsoft Office, SharePoint, and Ariba.

Preferred Qualifications:

• Proficiency with Revit, Bluebeam, building information modeling (BIM), and other industry-standard design / space-planning software.
• Experience coordinating laboratory programming with containment, mechanical, electrical, and plumbing (MEP) systems, casework, and equipment planning, and reviewing external consultant deliverables against approved programs.
• Experience with master planning and strategic portfolio planning across multi-site or geographically dispersed portfolios.

Physical/Mental Requirements:

• Primarily office-based role requiring use of standard office equipment and digital collaboration tools.
• Requires travel to R&D sites and periodic walkthroughs of office, laboratory, facility, and project environments.

Salary: The annual base salary for this position ranges from $124,400.00 to $207,400.00.

Benefits: We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

Job Data by YubHub.

You will work closely with the global clinical program lead and serve as a clinical lead for one or more studies within a clinical program.

Your responsibilities will include:

Accountable for safety across the study

• Providing medical advice for all medical issues during risk assessment and mitigation planning
• Ensuring development of and adherence to the Safety Surveillance Review Plan (SSRP)
• Monitoring study safety issues and providing input to serious adverse events (SAEs) reports
• Participating in the Safety Review Team to evaluate medical benefits/risks
• Reviewing literature as needed to respond to safety questions
• Communicating safety information to sites across the study

Protocol design and strategy

• Contributing towards medical input during protocol development and updates to the clinical development plan
• Working closely with other medical monitors to ensure documents meet regulatory requirements and company policy
• Providing medical input into country feasibility

Support study team

• Providing clinical input to protocol/study team for monitoring guidelines, statistics analysis plans, and data quality planning
• Contributing to contract research organization/vendor selection
• Working with study team to ensure high-quality data
• Contributing to medical review and interpretation of efficacy and safety data
• Providing protocol-specific training to study team, investigators, and clinical research associates
• Interacting with healthcare professionals at sites during the conduct of the study

Supports the program team

• Authoring clinical sections of regulatory documents
• Co-authoring abstracts, posters, presentations, and publications
• Contributing to budget execution of protocols

Interact with regulatory authorities, key opinion leaders, and principal investigators

• Supporting Clinical Regulatory Authority interactions
• Liaising with Key Opinion Leaders and Principal Investigators in countries

Basic qualifications:

• Medical degree (M.D./D.O. or equivalent)
• Licensed by a health authority to prescribe medicines (independent of supervision) for at least one year
• 0-4 years' work experience
• Ability to critically evaluate medical/scientific information
• Excellent written and oral communication
• Understanding of the design, development, and execution of clinical programs and studies
• Capacity to adapt to a fast-paced and changing environment
• Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot
• Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices

Preferred qualifications:

• Documented work experience/knowledge of statistics
• Training and experience in infectious diseases and/or infection control in the hospital setting
• Experience with investigational clinical trials

Additional details:

• Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week
• Annual base salary ranging from $189,200.00 to $315,400.00
• Eligible for participation in Pfizer's Global Performance Plan and share-based long-term incentive program
• Comprehensive benefits package, including 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits

Job Data by YubHub.