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Simulation in Respiratory and Inflammation (CPMS R&amp;I) at GSK is recruiting for a Director–level Clinical Pharmacologist with cardiovascular and metabolic disease expertise.</p>\n<p>This role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling.</p>\n<p>You will lead the end‑to‑end application of MIDD across the drug development lifecycle - from first‑in‑human studies through filing and lifecycle management - and provide clinical pharmacology strategy and evidence‑generation input.</p>\n<p>Main responsibilities and accountabilities include:</p>\n<ul>\n<li>Design &amp; Execute Model Informed and Clinical Pharmacology strategies</li>\n</ul>\n<p>Develop and implement robust MIDD &amp; ClinPharm evidence strategies to de risk and accelerate RIIRU programs.</p>\n<ul>\n<li>Ensure robust ways of working and regulatory ready evidence</li>\n</ul>\n<p>Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling.</p>\n<ul>\n<li>Build cross functional partnerships</li>\n</ul>\n<p>Work closely with CPQM peers and cross functional partners.</p>\n<ul>\n<li>External engagement &amp; 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