{"version":"0.1","company":{"name":"YubHub","url":"https://yubhub.co","jobsUrl":"https://yubhub.co/jobs/city/branford/"},"x-facet":{"type":"city","slug":"branford","display":"Branford","count":1},"x-feed-size-limit":100,"x-feed-sort":"enriched_at desc","x-feed-notice":"This feed contains at most 100 jobs (the most recently enriched). For the full corpus, use the paginated /stats/by-facet endpoint or /search.","x-generator":"yubhub-xml-generator","x-rights":"Free to redistribute with attribution: \"Data by YubHub (https://yubhub.co)\"","x-schema":"Each entry in `jobs` follows https://schema.org/JobPosting. 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This role will drive model-informed drug discovery across ViiV&#39;s Drug Discovery organization by developing and applying fit-for-purpose modeling and simulation approaches.</p>\n<p>The successful candidate will serve in a matrix leadership role, partnering closely with DMPK, Medicinal Chemistry, Biology, and Clinical Pharmacology to enable early dose predictions and guide the design and selection of high-quality clinical candidates.</p>\n<p>Responsibilities:</p>\n<ul>\n<li>Develop and apply fit-for-purpose mechanistic and translational models (PBPK, IVIVE, PK/PD) to guide drug discovery teams toward the highest-quality clinical candidates</li>\n<li>Translate complex ADME, PK, PD, and translational data into actionable insights for project teams and senior leadership</li>\n<li>Apply modeling expertise across diverse modalities, formulations, and routes of administration, including long-acting therapies</li>\n<li>Build scalable computational tools, workflows, and prototypes that accelerate discovery decisions and candidate optimization</li>\n<li>Establish best practices, standards, and governance for modeling methodologies, tools, and computational workflows</li>\n<li>Contribute to scientific publications, regulatory submissions, and other technical documentation, and represent ViiV externally through regulatory interactions and scientific thought leadership</li>\n</ul>\n<p>Requirements:</p>\n<ul>\n<li>Master&#39;s degree with 7 or more years of post-graduate experience, or a PhD with 4 or more years of post-graduate experience, supporting drug discovery programs from lead optimization to Phase I clinical studies</li>\n<li>Strong understanding of ADME principles and integration of standard DMPK workflows and data streams into empirical and mechanistic modeling and simulation approaches</li>\n<li>Demonstrated ability to apply modeling and simulation approaches to influence key drug discovery decisions</li>\n<li>Broad computational programming expertise in programming and modeling languages (e.g., R, Python) and modeling platforms (e.g., Simcyp, GastroPlus)</li>\n<li>Experience integrating diverse datasets into unified predictive modeling platforms</li>\n<li>Ability to interpret and communicate modeling results to cross-functional teams</li>\n</ul>\n<p>Preferred Qualifications:</p>\n<ul>\n<li>PhD with 6 or more years of drug discovery experience in DMPK or a related discipline</li>\n<li>Demonstrated experience developing and applying modeling and simulation strategies across diverse modalities and routes of administration</li>\n<li>Experience working across teams, including matrix and functional leadership</li>\n<li>Excellent written, verbal, and presentation skills</li>\n<li>Experience in infectious disease and/or immunology therapeutic areas</li>\n</ul>\n<p>Benefits:</p>\n<ul>\n<li>Annual base salary ranging from $141,075 to $235,125</li>\n<li>Annual bonus and eligibility to participate in share-based long-term incentive program</li>\n<li>Health care and other insurance benefits</li>\n<li>Retirement benefits</li>\n<li>Paid holidays, vacation, and paid caregiver/parental and medical leave</li>\n</ul>\n<p style=\"margin-top:24px;font-size:13px;color:#666;\">Job Data by <a href=\"https://yubhub.co\">YubHub</a>.</p>","url":"https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/USA---Connecticut---Branford/ViiV-Healthcare--GSK--Scientific-Leader--Pre-clinical-DMPK-Drug-Discovery-Modeling_447561-1","directApply":true,"hiringOrganization":{"@type":"Organization","name":"ViiV Healthcare (GSK)","sameAs":"https://gsk.com","logo":"https://logos.yubhub.co/gsk.com.png"},"x-apply-url":"https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/USA---Connecticut---Branford/ViiV-Healthcare--GSK--Scientific-Leader--Pre-clinical-DMPK-Drug-Discovery-Modeling_447561-1","x-work-arrangement":"hybrid","x-experience-level":"senior","x-job-type":"full-time","x-salary-range":"$141,075 to $235,125","x-skills-required":["ADME","PBPK Modeling","Pharmacokinetics","Pharmacology","Drug Discovery Process"],"x-skills-preferred":["infectious disease","immunology","matrix and functional leadership"],"x-benefits":["pension","paid_leave","bonus","relocation"],"x-licences":[],"x-visa-sponsorship":"unknown","x-visa-sponsorship-text":null,"x-work-authorisation":"unknown","x-work-authorisation-text":null,"datePosted":"2026-10-01T00:00:00.000Z","jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Branford, CT"}},"employmentType":"FULL_TIME","occupationalCategory":"Healthcare","industry":"Healthcare","skills":"ADME, PBPK Modeling, Pharmacokinetics, Pharmacology, Drug Discovery Process, infectious disease, immunology, matrix and functional leadership","baseSalary":{"@type":"MonetaryAmount","currency":"USD","value":{"@type":"QuantitativeValue","minValue":141075,"maxValue":235125,"unitText":"YEAR"}}}]}